"At least half of all cancers in the United States are diagnosed in Stage III and Stage IV, leading to lower survival rates. Detecting cancer at the earliest stages dramatically increases the probability of a cure and long-term survival." - Huge potential here.
I believe GRAIL is poised for rapid global scale. It imposes no limitation to how many times a person can go for screening as their screening is free from radiation exposures and invasive procedures. Good luck.
I think it's unfortunate that the website doesn't have a "HOW can consumers access" section. I imagine a lot of people concerned about cancer are wondering what to do next.
@flanaganlyfe great article thanks! One of the major problems historically is that the DNA mutations that are released are very trace, I've heard the analogy "needle in the haystack" more than once. Hopefully they can make their test something routine like a paps exam, now if we could get insurance on board :(
Hmm... if you can detect cancerous DNA markers in the bloodstream, it may be too late (with the exception of hematological cancers etc). Ideally you want to catch tumors growing in local tissue environments (i.e. stage 1-2) before they reach the lymphatic and circulatory system.
That said, it might be a useful tool if the DNA markers are treated as a prognostic indicator for treatment, or even detecting cancer subtypes.
I will be interested in reading the papers this tech is based on (not sure if they can detect a few specific cancers or most/all cancers). If they can really do this it will be very helpful, but of course detection is only one step toward treatment/cure - but the earlier you detect cancer the better.
A very good initiative. But what matters most is what will be the pricing for a single test. If it ends up being priced like the BRCA1 and BRCA2 gene mutations test then point is lost.
One other thought is the psychological impact of such a test. There is a very good possibility that most people who takes this test might end up being positive for some sort of cancer. Although you might not have contracted cancer you might end being treating yourself like one, right?
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